After Dr. Octopus releases a swarm of octobots at the heroes, start beating them up until the attack ends.
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Minikit 01/10 – Magnetism:
Behind the safe door on the back wall of the area. Use a magnetic based character (eg: Magneto) to rip the door of and access the first minikit.
Minikit 02/10 – Explosives + Electricity:
In between the two pods on the far right of the room is a silver lego blocking the way. Use an explosives character (eg: Iron Man) to blast it away. This will reveal an electrical panel, use an electricity based character (eg: Thor) to open it up and retrieve the second minikit inside.
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To the right and above of where you began is a transform plate that Mr Fantastic can use to turn into a handy (but extremely situational) form. Turn into a screwdriver to remove the lock on the Shield Switch. Now the switch is unlocked, Captain America can activate it by throwing his shield inside. This activates the small platform lift next to it.
Head up the platform lift and Dr. Octopus will head for the roof, showering down flames on the walkway in front of Captain America. Use your shield to douse the flames and walk across to the left side of the area before dropping down. More octobots will attack but can be easily dealt with by Captain America.
To get Mr Fantastic across, construct the wall grille from the debris that Dr. Octopus left in his wake (next to the giant 4 emblem on the ground). This will allow him to travel over to the left area.
Grab the grapple point with Mr Fantastic's long arms to remove the cover on the wall. Construct the cover pieces to create a shield switch for Captain America. Activate it with the Captain to power the giant drill. The controls are behind a small door up the nearby ladder. Use Mr Fantastic to activate them and steer the drill into the wall socket.
This will make a laser turret appear with a big red switch next to it. Hop on the switch and jump back to the previous area with Captain America. The laser will destroy an object but that's ok as you can reconstruct it into a special deflection platform for Captain America.
Place the Captain on it and activate shield mode to begin bouncing the laser back. The targets you need to hit with it are the two light blue circles to the left and right from where the laser will initially hit the wall. Charge both of them up to full and the giant four emblem will open up to reveal your mode of transportation. Strap yourself in to reach the roof.
Dr. Octopus will be wreaking havoc on the rooftop above, but will move away as the heroes arrive.
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Minikit 03/10 – Dig spot + Power cosmic:
Once you reach the roof on the flying elevator, there will be a dig spot at the front left side of the screen. Dig away with a clawed hero (eg: Wolverine) to reveal cosmic bricks. Use a character with the power cosmic (eg: Galactus) to assemble the rocket and the third minikit will appear.
Minikit 04/10 – Mutate five rooftop gardens:
As you progress through the rooftop sections there will be five ordinary rooftop gardens. The heroes can activate these, forcing the flowers to grow rapidly. The first is immediately after the first big gap (which in story mode you would have to glide across as Mr Fantastic). The second is on the rooftop up and to the right of the prior one (above the giant fans). The third one is on the next building across where Dr. Octopus breaks apart the walls, creating a ramp and small fires. The fourth and fifth ones are on the next rooftop (which you can reach by wall jumping/ flying or activating the elevator), after all the plants have grown the fourth minikit will spawn.
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In the middle of the area will be a large gap. Use Mr Fantastic's glide abilities to get across. There will be a stretch point/ handle above where you land and from the pieces you can construct a ladder to reach the offices. Climb up and travel to the end of the offices to reach some green and red objects. Smash them and build the pieces to add a pushing surface to the post. This allows Mr Fantastic to swivel the large dish on the roof above.
Thanks to his acrobatic skills, Captain America can now flip his way across the poles to reach the same side as Mr Fantastic. On the far side of this area will be a shield switch for the Captain to activate. This turns off the fans on the lower level and allows Mr Fantastic to reach the upper area. Nearby are some blue pipes that can be destroyed and turned into a transformation plate for Mr Fantastic.
Hop on and Mr Fantastic will turn into a pump, exploding the water tower above. The pieces of the tower can be reassembled into a rope across the gap (where Dr. Octopus has been taunting you all this time), slide across to meet the doctor.
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Minikit 05/10 – Explosives + Symbiote:
After crossing over to Dr. Octopus (and getting slapped around a bit), you will see on the wall next to where he was standing is a silver lego vent. Blow it up with an explosives hero (eg: Hawkeye). This will create a black puddle of symbiote goo. Use a symbiote character to teleport into the enclosed greenhouse nearby and grab the fifth minikit.
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Hit the doctor once to release the other hero and he will flee once again, damaging buildings and generally causing mayhem. Octobots will also swarm you here, so take a few seconds to deal with them. Climb up to where the doctor is laughing at you from and he will drop off the building.
Only to re-emerge on the other side of the gap. Use Captain America's shield to hit the right bottom corner of the large red neon sign. This will damage the sign, revealing a second weak spot on the other side. Break this one as well and the sign will fall across the gap making a handy bridge.
More octobots will be waiting on the other side. Climb up to the area behind the glass windows to spot a flaming barrier, blocking a wall jump path for Captain America and on the left side a grapple point for Mr Fantastic. On the roof, smash the blue box on the right side to give you the pieces for another shield switch.
Once activated it will power on the lift for Mr Fantastic. An octobot will be waiting inside. Glide across the gap with Mr Fantastic to the next rooftop. More octobots will impede your progress for a few seconds. Use the newly destroyed parts to create the other end of the rope line for Captain America.
Above you on the Daily Bugle, Dr. Octopus will be lazily swinging his tentacles back and forth. Use the vent on the right side of the area to reach the ledge with Mr Fantastic. Move underneath Dr. Octopus and "throw" your arm at his body. Once again he will make a break for it (although the wrecking ball is hilarious).
On a new rooftop, the chase resumes. Head to the middle rooftop and use Mr Fantastic to grapple the tower across the gap and bring it crashing down. This will give you access to the adjacent roof. Octobots will be waiting. Finish them. Use Spider-man's spider sense to detect the climbable wall to the left. Head up and fight some more octobots. Use spider sense to detect the two web handles to pull which will turn on the fans below.
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Stan Lee: Explosives + Flight + Telekinesis:
After activating the large fans, you may notice the silver lego bricks on the highest part of the roof above our heroes. Fly up with an explosives character (eg: Iron Man – Mark 6) and blow the blocks away. The loose blocks can be made into a pipe that connects to the water tower. Use a telekinetic character with flight (eg: Galactus) to turn the handle and reveal Stan Lee.
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A computer panel on the far right of this upper area can only be activated by Mr Fantastic so use the fans to get him up there. Use the panel to open the gate and enter the rooftop garden.
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Minikit 06/10 – Explosives + Mr. Fantastic:
In the large rooftop garden area there will be several silver lego objects next to the lego turf. Use an explosives hero (eg: Iron Man – Mark 6) to dismantle them. Construct the fallen pieces into a large bellows/ spring and start jumping on it to bring a Fantastic 4 change plate to the surface of the pond. Use Mr Fantastic to mow the grass (yes, seriously) and the sixth minikit will materialize.
Minikit 07/10 – Gold barrier + Captain America:
In the back right corner of the garden area is a gold canister next to a barbeque. Use a flame based hero (eg: The Human Torch) to burn away the cannister and destroy the barbeque. The newly created minikit will be surrounded by flames, use Captain America's shield ability to reach it safely.
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A transform panel on the other side of the garden will turn Mr Fantastic into a rocket, blowing apart the Spider-man billboard and revealing two grapple points. Grab and pull with Mr Fantastic to bring it down completely for another bridge. The doctor will taunt you once again and proceed to helicopter a building (you read that right). Follow him through the new hole to face off with the octopus.
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Boss: Doctor Octopus
Attacks:
Grapple – Dr. Octopus will grab a nearby character and rend them limb from limb. Stay back when he is not stuck to avoid this attack. A one hit KO if you get too close.
Stomp – As he moves Dr. Octopus will stomp the ground occasionally. Move out of his way as he travels to avoid this. Deals one heart of damage.
Cracking up – Dr. Octopus will stomp the ground sending a crack towards the controlled hero. Keep mobile or jump to avoid this attack. Deals one heart of damage.
Summon octobots – Constantly during the fight octobots will appear and begin attacking everyone in sight. They are infinite so don't try to kill them all.
Finally after all this chasing, Dr Octopus will take you on.
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Minikit 08/10 – Green handles:
During the Dr. Octopus battle there will be a vehicle on the left side of the area that can be broken apart by a character with super strength (eg: The Hulk). Break it open to reveal the eighth minikit.
Minikit 09/10 – Gold barrier:
Five fire hydrants with golden tops are scattered around this small area. Use a fire based hero (eg: The Human Torch), track them down and destroy them to find the ninth minikit. Two are on the left side of the area and three are on the right.
Minikit 10/10 – Explosives + Smash:
Underneath a silver car (use an explosives hero such as Iron Man – Mark 6 to clear) in the far right corner of the area is a smashable ground panel. Use a big hero (eg: The Hulk) to smash the panel and obtain the final minikit.
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The tentacles of Doctor Octopus are his weakness here, when he attacks or smashes the ground he will occasionally get one stuck. All you need to do is move a character over to the stuck tendril and press X to damage it. This will deal one point of damage to the doctor.
Spider-man is the best for this process as he can web swing above the doctor (triggering his attacks) until the doctor gets stuck and then deliver the damaging blow. After repeating this method two more times the doctor will flee once again but only requires a single connecting hit to finish. Run over to him and slug him once in the jaw to end this simple fight.
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True believer (170,000 studs): Collect the specified number of studs during the level to obtain a gold brick.