It's not enough for Madhosue Mode to have more monsters, less ammo, and fewer saves- they also gotta mixup where all your stuff is kept. Here's the key to where everything is now, and to which things are just as you left them.
Unchanged:
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All video locations and flashbacks remain the same, though the enemies in the final flashback are tougher.
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The locations of Journal Entries & Mr. Everywhere Bobbleheads are unchanged.
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All Treasure Photos are found in the same place, and yield the same treasures as before
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All special key doors (Scorpion, Crow & Snake) are in the same places, leading to the same rooms. The Crow and Snake Keys are in the same places as before (The Scorpion Key is now in a coin cage in the Main Hall).
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The access cards are in the same places, and obtained the same way as before.
Weapon Locations
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The knife you still get from the deputy, but it's a mere toothpick next to the Circular Saw
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The G-17 is still in the garage, but it's now lying where the deputy fell, rather than in the backseat of the car.
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The M-19 is now in the Greenhouse entry, rather than in Zoe's Trailer
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The Grenade Launcher is now in Zoe's Trailer, rather than in the Crow Room of the Main House.
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The two shotguns are in the same places, but the Model Shotgun in now is the Dissection Room- you can grab it when you make for the third dogshead here.
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The flamethrower components are in the same places.
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The Survival Knife is now stuck in a ping-pong table in the Recreation Room
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The MPM Handgun is now in Sickbay
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The Machine Gun and key are in the same places.